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Article

MDM2 and HIF1alpha expression levels in different histologic subtypes of malignant pleural mesothelioma: correlation with pathological and clinical data.

Oncotarget - 8 Dec 2015

Pasello Giulia, Urso Loredana, Mencoboni Manlio, Grosso Federica, Ceresoli Giovanni Luca, Lunardi Francesca, Vuljan Stefania Edith, Bertorelle Roberta, Sacchetto Valeria, Ciminale Vincenzo, Rea Federico, Favaretto Adolfo, Conte PierFranco, Calabrese Fiorella

Abstract excerpt

Malignant pleural mesothelioma (MPM) is an aggressive tumor with poor prognosis and limited treatment options. Sarcomatoid/biphasic mesotheliomas are characterized by more aggressive behaviour and a poorer prognosis compared with the epithelioid subtype. To date prognostic and tailored therapeutic biomarkers are lacking. The present study analyzed the expression levels of MDM2 and HIF1alpha in different...

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Source

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Identifiers

PMID: 26544728
DOI: 10.18632/oncotarget.5974
PMCID: PMC4747209

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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