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Article

Characterisation of lung macrophage subpopulations in COPD patients and controls.

Scientific reports - 2 Aug 2017

Dewhurst Jennifer A, Lea Simon, Hardaker Elizabeth, Dungwa Josiah V, Ravi Arjun K, Singh Dave

Abstract excerpt

Lung macrophage subpopulations have been identified based on size. We investigated characteristics of small and large macrophages in the alveolar spaces and lung interstitium of COPD patients and controls. Alveolar and interstitial cells were isolated from lung resection tissue from 88 patients. Macrophage subpopulation cell-surface expression of immunological markers and phagocytic ability were assessed by flow...

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Share to Chemokine CXCL1
Share to Immunohistochemistry
Share to Macrophages, Alveolar

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phagocytosis

Share to Pulmonary Disease, Chronic Obstructive

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Identifiers

PMID: 28769058
DOI: 10.1038/s41598-017-07101-2
PMCID: PMC5540919

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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