Article
Detection of Drug Resistance Mutations in the Reverse Transcriptase Gene of HIV-1-Infected North Indian Population Failing First-Line Antiretroviral Therapy "A Follow-Up Cohort Study".
AIDS research and human retroviruses - 1 Oct 2021
Barik Sushanta Kumar, Bansal Avi Kumar, Mohanty Partha Sarathi, Tripathy Srikanth Prasad, Hanna Luke Elizabeth, Karunaianantham Ramesh, Pattabiraman Sathyamoorthy, Singh Tej Pal, Tandon Rekha, Tomar Sheetal, Jena Srikanta, Patil Shripad A, Mohanty Keshar Kunja
Abstract excerpt
We aim to characterize the drug resistance mutations in reverse transcriptase gene of HIV-1 subtype C-infected North Indian population in those who are failing first-line antiretroviral therapy (ART) and if these mutations are associated with mortality. We also attempted the assessment of switch over to second-line antiretroviral therapy in these patients. Based on the immunological marker CD4 count (<350...
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