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Article

The E3 ubiquitin ligase MID1/TRIM18 promotes atypical ubiquitination of the BRCA2-associated factor 35, BRAF35.

Biochimica et biophysica acta. Molecular cell research - 1 Oct 2017

Zanchetta Melania E, Napolitano Luisa M R, Maddalo Danilo, Meroni Germana

Abstract excerpt

MID1/TRIM18 is a member of the TRIM family of ubiquitin E3 ligases characterized by the presence of a conserved RING-containing N-terminal tripartite motif. Mutations in the MID1 gene have been associated with the X-linked form of Opitz Syndrome, a developmental disorder characterized by midline defects and intellectual disability. The effect of MID1 E3 ligase activity within the cell and the role in the...

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Source

Identifiers

PMID: 28760657
DOI: 10.1016/j.bbamcr.2017.07.014

Genes

MID1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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