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Article

Differential Methylation of lncRNA KCNQ1OT1 Promoter Polymorphism was Associated with Symptomatic Cardiac Long QT

27 Jul 2017

Abstract excerpt

AIM: To investigate whether the differential methylation of KCNQ1OT1 was associated with the risk of symptomatic long QTc. PATIENTS & METHODS: We investigated the methylation status of KCNQ1OT1 in a cohort of patients (n = 131) with a symptomatic prolonged QTc. All the patients were genotyped for a common promoter polymorphism (rs11023840). They were also genotyped for DNA digested with the methylation-sensitive...

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PMID: 28749187
DOI: 10.2217/epi-2017-0024

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