Article
lncRNAs in development and disease: from functions to mechanisms.
Open biology - 1 Jul 2017
Delás M Joaquina, Hannon Gregory J
Abstract excerpt
Differential expression of long non-coding RNAs (lncRNAs) during differentiation and their misregulation in cancer highlight their potential as cell fate regulators. While some example lncRNAs have been characterized in great detail, the functional in vivo relevance of others has been called into question. Finding functional lncRNAs will most probably require a combination of complementary approaches that will...
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