Article
Association of IL-10-Regulating MicroRNAs in Peripheral Blood Mononuclear Cells with the Pathogenesis of Autoimmune Thyroid Disease.
Immunological investigations - 1 Aug 2017
Takuse Yukina, Watanabe Mikio, Inoue Naoya, Ozaki Ritsuko, Ohtsu Hiroshi, Saeki Minori, Katsumata Yuka, Hidaka Yoh, Iwatani Yoshinori
Abstract excerpt
Interleukin (IL)-10 is known to suppress inflammation in autoimmune diseases. IL-10 can be regulated by miRNAs. To elucidate the involvement of miRNAs that regulate IL-10 expression with the pathogenesis of autoimmune thyroid disease (AITD), we examined the expression levels of hsa-miR-27a-3p, hsa-miR-98-5p, hsa-miR-106a-5p, and hsa-miR-223-3p in peripheral blood mononuclear cells (PBMCs) from 43 patients with...
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