Article
The DCDC2 deletion is not a risk factor for dyslexia.
Translational psychiatry - 25 Jul 2017
Scerri T S, Macpherson E, Martinelli A, Wa W C, Monaco A P, Stein J, Zheng M, Suk-Han Ho C, McBride C, Snowling M, Hulme C, Hayiou-Thomas M E, Waye M M Y, Talcott J B, Paracchini S
Abstract excerpt
Dyslexia is a specific impairment in learning to read and has strong heritability. An intronic deletion within the DCDC2 gene, with ~8% frequency in European populations, is increasingly used as a marker for dyslexia in neuroimaging and behavioral studies. At a mechanistic level, this deletion has been proposed to influence sensory processing capacity, and in particular sensitivity to visual coherent motion. Our...
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