Article
DNA damage and the bystander response in tumor and normal cells exposed to X-rays.
Mutation research. Genetic toxicology and environmental mutagenesis - 1 Sept 2017
Subhashree M, Venkateswarlu R, Karthik K, Shangamithra V, Venkatachalam P
Abstract excerpt
Monolayer and suspension cultures of tumor (BMG-1, CCRF-CEM), normal (AG1522, HADF, lymphocytes) and ATM-mutant (GM4405) human cells were exposed to X-rays at doses used in radiotherapy (high dose and high dose-rate) or radiological imaging (low dose and low dose-rate). Radiation-induced DNA damage, its persistence, and possible bystander effects were evaluated, based on DNA damage markers (γ-H2AX, p53ser15) and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
