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Article

Adaptive evolution of a hyperthermophilic archaeon pinpoints a formate transporter as a critical factor for the growth enhancement on formate.

Scientific reports - 21 Jul 2017

Jung Hae-Chang, Lee Seong Hyuk, Lee Sung-Mok, An Young Jun, Lee Jung-Hyun, Lee Hyun Sook, Kang Sung Gyun

Abstract excerpt

Previously, we reported that the hyperthermophilic archaeon Thermococcus onnurineus NA1 could grow on formate and produce H2. Formate conversion to hydrogen was mediated by a formate-hydrogen lyase complex and was indeed a part of chemiosmotic coupling to ATP generation. In this study, we employed an adaptation approach to enhance the cell growth on formate and investigated molecular changes. As serial transfer...

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Identifiers

PMID: 28733620
DOI: 10.1038/s41598-017-05424-8
PMCID: PMC5522443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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