Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Adaptive engineering of a hyperthermophilic archaeon on CO and discovering the underlying mechanism by multi-omics analysis.

Scientific reports - 15 Mar 2016

Lee Seong Hyuk, Kim Min-Sik, Lee Jae-Hak, Kim Tae Wan, Bae Seung Seob, Lee Sung-Mok, Jung Hae Chang, Yang Tae-Jun, Choi Ae Ran, Cho Yong-Jun, Lee Jung-Hyun, Kwon Kae Kyoung, Lee Hyun Sook, Kang Sung Gyun

Abstract excerpt

The hyperthermophilic archaeon Thermococcus onnurineus NA1 can grow and produce H2 on carbon monoxide (CO) and its H2 production rates have been improved through metabolic engineering. In this study, we applied adaptive evolution to enhance H2 productivity. After over 150 serial transfers onto CO medium, cell density, CO consumption rate and H2 production rate increased. The underlying mechanism for those...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carbon Monoxide
Share to Energy Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenomics

Share to Genes, Archaeal

Share to Genome, Archaeal

Share to Hot Temperature

Share to Hydrogen

Share to Metabolic Engineering

Source

Open in PubMed Open full text

Identifiers

PMID: 26975345
DOI: 10.1038/srep22896
PMCID: PMC4791640

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Adaptive engineering of a hyperthermophilic archaeon on CO and discovering the underlying mechanism by multi-omics analysis.PMID 26975345Read ↗

Transcriptomic profiling and its implications for the H2 production of a non-methanogen deficient in the frhAGB-encoding hydrogenase.Semantic proximity Read ↗

Adaptive evolution of a hyperthermophilic archaeon pinpoints a formate transporter as a critical factor for the growth enhancement on formate.Semantic proximity Read ↗

An archaeal transcription factor EnfR with a novel 'eighth note' fold controls hydrogen production of a hyperthermophilic archaeon Thermococcus onnurineus NA1.Semantic proximity Read ↗

Genome-scale metabolic reconstruction and hypothesis testing in the methanogenic archaeon Methanosarcina acetivorans C2A.Semantic proximity Read ↗

Integration of strain and process optimization to increase autotrophic growth of engineered Komagataella phaffii.Semantic proximity Read ↗

Energy conservation by oxidation of formate to carbon dioxide and hydrogen via a sodium ion current in a hyperthermophilic archaeon.Semantic proximity Read ↗

Systems-level analysis identifies protein-RNA interactions contributing to autotrophy of <i>Clostridium autoethanogenum</i>Semantic proximity Read ↗

Application of transposon-insertion sequencing to determine gene essentiality in the acetogen <i>Clostridium autoethanogenum</i>Semantic proximity Read ↗

CO synthesized from the central one-carbon pool as source for the iron carbonyl in O2-tolerant [NiFe]-hydrogenase.Semantic proximity Read ↗

A single transcription factor regulates evolutionarily diverse but functionally linked metabolic pathways in response to nutrient availability.Semantic proximity Read ↗

Long-Term m5C Methylome Dynamics Parallel Phenotypic Adaptation in the Cyanobacterium Trichodesmium.Semantic proximity Read ↗

Atmospheric chemosynthesis is phylogenetically and geographically widespread and contributes significantly to carbon fixation throughout cold desertsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.