Article
Identification of differential co-expressed gene networks in early rheumatoid arthritis achieving sustained drug-free remission after treatment with a tocilizumab-based or methotrexate-based strategy.
Arthritis research & therapy - 20 Jul 2017
Teitsma Xavier M, Jacobs Johannes W G, Mokry Michal, Borm Michelle E A, Pethö-Schramm Attila, van Laar Jacob M, Bijlsma Johannes W J, Lafeber Floris P J
Abstract excerpt
BACKGROUND: Methotrexate is endorsed to be used as first-line treatment in rheumatoid arthritis (RA). However, a large proportion of patients need additional treatment with a biological disease-modifying anti-rheumatic drug (DMARD) to adequately suppress their disease activity. A better understanding of genotypes could help to distinguish between patients with different pathogenic mechanisms. The aim of this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.