Molecular epidemiology and clinical characteristics of carbapenem-resistant Klebsiella pneumoniae bloodstream and pneumonia isolates

Abstract excerpt

ABSTRACT Appropriate antibiotic therapy in patients with carbapenem-resistant Klebsiella pneumoniae (CRKp) infections often requires knowledge of resistance mechanisms. Therefore, we aimed to define the clonal diversity, mechanisms of carbapenem resistance, potential for carbapenem resistance transmissibility, virulence gene repertoire, and potential clinical impact of these genetic elements in patients with CRKp...