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Article

Oncogenic transformation of lung cells results in distinct exosome protein profile similar to the cell of origin.

Proteomics - 1 Dec 2017

Lobb Richard J, Hastie Marcus L, Norris Emma L, van Amerongen Rosa, Gorman Jeffrey J, Möller Andreas

Abstract excerpt

Lung cancer is responsible for the highest rate of cancer mortality worldwide. Lung cancer patients are often ineligible for tumor biopsies due to comorbidities. As a result, patients may not have the most effective treatment regimens administered. Patients with mutations in the epidermal growth factor receptor (EGFR) have improved survival in response to EGFR tyrosine kinase inhibitors. A noninvasive method of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28722786
DOI: 10.1002/pmic.201600432

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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