Article
ETV6 Gene Rearrangements Characterize a Morphologically Distinct Subset of Sinonasal Low-grade Non-intestinal-type Adenocarcinoma: A Novel Translocation-associated Carcinoma Restricted to the Sinonasal Tract.
The American journal of surgical pathology - 1 Nov 2017
Andreasen Simon, Skálová Alena, Agaimy Abbas, Bishop Justin A, Laco Jan, Leivo Ilmo, Franchi Alessandro, Larsen Stine R, Erentaite Daiva, Ulhøi Benedicte P, von Buchwald Christian, Melchior Linea C, Michal Michal, Kiss Katalin
Abstract excerpt
Low-grade sinonasal adenocarcinomas (low-grade SNACs) of the sinonasal tract comprise a poorly characterized and histologically heterogeneous group of tumors. We describe three cases of a histologically distinct variant of low-grade SNAC characterized by ETV6 gene rearrangements. The patients included 2 women (aged 32 and 88 y) and a man (aged 75 y); all were initially treated with surgery alone. Follow-up ranged...
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