Molecular Profiling of Mammary Analog Secretory Carcinoma Revealed a Subset of Tumors Harboring a Novel ETV6-RET Translocation: Report of 10 Cases.

doi:10.1097/PAS.0000000000000972

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Article

Molecular Profiling of Mammary Analog Secretory Carcinoma Revealed a Subset of Tumors Harboring a Novel ETV6-RET Translocation: Report of 10 Cases.

The American journal of surgical pathology - 1 Feb 2018

Skalova Alena, Vanecek Tomas, Martinek Petr, Weinreb Ilan, Stevens Todd M, Simpson Roderick H W, Hyrcza Martin, Rupp Niels J, Baneckova Martina, Michal Michael, Slouka David, Svoboda Tomas, Metelkova Alena, Etebarian Arghavan, Pavelka Jaroslav, Potts Steven J, Christiansen Jason, Steiner Petr, Michal Michal

Abstract excerpt

ETV6 gene abnormalities are well described in tumor pathology. Many fusion partners of ETV6 have been reported in a variety of epithelial, mesenchymal, and hematological malignancies. In salivary gland tumor pathology, however, the ETV6-NTRK3 translocation is specific for (mammary analog) secretory carcinoma, and has not been documented in any other salivary tumor type. The present study comprised a clinical,...

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Share to ETS Translocation Variant 6 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to In Situ Hybridization, Fluorescence

Share to Proto-Oncogene Proteins c-ets

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Identifiers

PMID: 29076873
DOI: 10.1097/PAS.0000000000000972

Genes

ETV6
RET
NTRK3

Provenance

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