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Article

Clinical features and mutation spectrum in Chinese patients with CADASIL: A multicenter retrospective study.

CNS neuroscience & therapeutics - 1 Sept 2017

Chen Sheng, Ni Wang, Yin Xin-Zhen, Liu Han-Qiu, Lu Cong, Zheng Qiao-Juan, Zhao Gui-Xian, Xu Yong-Feng, Wu Lei, Zhang Liang, Wang Ning, Li Hong-Fu, Wu Zhi-Ying

Abstract excerpt

AIM: To characterize clinical features and mutation spectrum in Chinese patients with CADASIL. METHODS: We collected 261 clinically suspected Chinese CADASIL patients from three hospitals located in different regions of China. Sanger sequencing is performed to screen the exons 2 to 24 of NOTCH3 gene. Clinical and genetic data were retrospectively studied. Haplotype analyses were performed in patients carrying...

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Identifiers

PMID: 28710804
DOI: 10.1111/cns.12719
PMCID: PMC6492642

Genes

NOTCH3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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