Article
Linc-DYNC2H1-4 promotes EMT and CSC phenotypes by acting as a sponge of miR-145 in pancreatic cancer cells.
Cell death & disease - 13 Jul 2017
Gao Yuran, Zhang Zhicheng, Li Kai, Gong Liying, Yang Qingzhu, Huang Xuemei, Hong Chengcheng, Ding Mingfeng, Yang Huanjie
Abstract excerpt
The acquisition of epithelial-mesenchymal transition (EMT) and/or existence of a sub-population of cancer stem-like cells (CSC) are associated with malignant behavior and chemoresistance. To identify which factor could promote EMT and CSC formation and uncover the mechanistic role of such factor is important for novel and targeted therapies. In the present study, we found that the long intergenic non-coding RNA...
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