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Article

Neither eosinophils nor neutrophils require ATG5-dependent autophagy for extracellular DNA trap formation.

Immunology - 1 Nov 2017

Germic Nina, Stojkov Darko, Oberson Kevin, Yousefi Shida, Simon Hans-Uwe

Abstract excerpt

The importance of extracellular traps (ETs) in innate immunity is well established, but the molecular mechanisms responsible for their formation remain unclear and in scientific dispute. ETs have been defined as extracellular DNA scaffolds associated with the granule proteins of eosinophils or neutrophils. They are capable of killing bacteria extracellularly. Based mainly on results with phosphoinositide 3-kinase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28703297
DOI: 10.1111/imm.12790
PMCID: PMC5629432

Genes

ATG5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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