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Article

FANCM mutation c.5791C>T is a risk factor for triple-negative breast cancer in the Finnish population.

Breast cancer research and treatment - 1 Nov 2017

Kiiski Johanna I, Tervasmäki Anna, Pelttari Liisa M, Khan Sofia, Mantere Tuomo, Pylkäs Katri, Mannermaa Arto, Tengström Maria, Kvist Anders, Borg Åke, Kosma Veli-Matti, Kallioniemi Anne, Schleutker Johanna, Bützow Ralf, Blomqvist Carl, Aittomäki Kristiina, Winqvist Robert, Nevanlinna Heli

Abstract excerpt

PURPOSE: The FANCM c.5101C>T nonsense mutation was previously found to associate with breast cancer in the Finnish population, especially among triple-negative cases. Here, we studied the prevalence of three other FANCM variants: c.5791C>T, which has been reported to predispose to familial breast cancer, and the c.4025_4026delCT and c.5293dupA variants recently identified in Finnish cancer patients. METHODS: We...

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Source

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Identifiers

PMID: 28702895
DOI: 10.1007/s10549-017-4388-0
PMCID: PMC5645429

Genes

FANCM
BRCA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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FANCM mutation c.5791C>T is a risk factor for triple-negative breast cancer in the Finnish population.PMID 28702895Read ↗

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