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Article

Recurrent BRAF Gene Rearrangements in Myxoinflammatory Fibroblastic Sarcomas, but Not Hemosiderotic Fibrolipomatous Tumors.

The American journal of surgical pathology - 1 Nov 2017

Kao Yu-Chien, Ranucci Valentina, Zhang Lei, Sung Yun-Shao, Athanasian Edward A, Swanson David, Dickson Brendan C, Antonescu Cristina R

Abstract excerpt

Myxoinflammatory fibroblastic sarcoma (MIFS) is a low grade soft tissue sarcoma with a predilection for acral sites, being associated with a high rate of local recurrence but very infrequent distant metastases. Although a t(1;10) translocation resulting in TGFBR3-MGEA5 fusion has been reported as a recurrent genetic event in MIFS, this abnormality is seen only in a subset of cases. As no studies to date have...

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Source

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Identifiers

PMID: 28692601
DOI: 10.1097/PAS.0000000000000899
PMCID: PMC5636656

Genes

BRAF
TGFBR3
VGLL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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