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Article

A global evolutionary and metabolic analysis of human obesity gene risk variants.

Gene - 5 Sept 2017

Castillo Joseph J, Hazlett Zachary S, Orlando Robert A, Garver William S

Abstract excerpt

It is generally accepted that the selection of gene variants during human evolution optimized energy metabolism that now interacts with our obesogenic environment to increase the prevalence of obesity. The purpose of this study was to perform a global evolutionary and metabolic analysis of human obesity gene risk variants (110 human obesity genes with 127 nearest gene risk variants) identified using genome-wide...

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Share to Evolution, Molecular
Share to Genetic Predisposition to Disease
Share to Genome, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Metabolic Networks and Pathways

Share to Obesity

Share to Polymorphism, Genetic

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Identifiers

PMID: 28687331
DOI: 10.1016/j.gene.2017.07.002
PMCID: PMC5558862

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