Article
Promoter hypomethylation of microRNA223 gene is associated with atherosclerotic cerebral infarction.
Atherosclerosis - 1 Aug 2017
Li Zhibin, Yu Fang, Zhou Xiaoqing, Zeng Sian, Zhan Qiong, Yuan Mei, Yang Qidong, Liu Yunhai, Xia Jian
Abstract excerpt
BACKGROUND AND AIMS: microRNA223 (miR-223) plays an important role in the development of atherosclerosis and ischemic stroke. It is involved in regulation of multiple physiological and pathophysiological processes such as cholesterol metabolism, endothelial cell (EC) function, and thrombosis. Here we investigated the role of methylation regulation of MIR-223 promoter region in atherosclerotic cerebral infarction...
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