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Article

Selective breeding and selection mapping using a novel wild-derived heterogeneous stock of mice revealed two closely-linked loci for tameness.

Scientific reports - 4 Jul 2017

Matsumoto Yuki, Goto Tatsuhiko, Nishino Jo, Nakaoka Hirofumi, Tanave Akira, Takano-Shimizu Toshiyuki, Mott Richard F, Koide Tsuyoshi

Abstract excerpt

Tameness is a major behavioral factor for domestication, and can be divided into two potential components: motivation to approach humans (active tameness) and reluctance to avoid humans (passive tameness). We identified genetic loci for active tameness through selective breeding, selection mapping, and association analysis. In previous work using laboratory and wild mouse strains, we found that laboratory strains...

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Identifiers

PMID: 28676693
DOI: 10.1038/s41598-017-04869-1
PMCID: PMC5496859

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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