Article
Symptom dimensions in OCD: item-level factor analysis and heritability estimates.
Behavior genetics - 1 Jul 2010
Katerberg Hilga, Delucchi Kevin L, Stewart S Evelyn, Lochner Christine, Denys Damiaan A J P, Stack Denise E, Andresen J Michael, Grant J E, Kim Suck W, Williams Kyle A, den Boer Johan A, van Balkom Anton J L M, Smit Johannes H, van Oppen Patricia, Polman Annemiek, Jenike Michael A, Stein Dan J, Mathews Carol A, Cath Danielle C
Abstract excerpt
To reduce the phenotypic heterogeneity of obsessive-compulsive disorder (OCD) for genetic, clinical and translational studies, numerous factor analyses of the Yale-Brown Obsessive Compulsive Scale checklist (YBOCS-CL) have been conducted. Results of these analyses have been inconsistent, likely as a consequence of small sample sizes and variable methodologies. Furthermore, data concerning the heritability of the...
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