Article
Cognition in mouse models of schizophrenia susceptibility genes.
Schizophrenia bulletin - 1 Mar 2010
Arguello P Alexander, Gogos Joseph A
Abstract excerpt
Cognitive deficits are core features of psychiatric disorders and contribute substantially to functional outcome. It is still unclear, however, how cognitive deficits are related to underlying genetic liability and overt clinical symptoms. Fortunately, animal models of susceptibility genes can illuminate how the products of disease-associated genetic variants affect brain function and ultimately alter behavior....
Topics
- Alleles
- Animals
- Brain
- Cognition Disorders
- Disease Models, Animal
- Executive Function
- Genetic Association Studies
- Genetic Markers
- Genetic Predisposition to Disease
- Humans
- Memory, Short-Term