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[Results and promises of genetics of cognitive impairment in schizophrenia: molecular-genetic approaches].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2000

Alfimova M V, Kondratiev N V, Golimbet V E

Abstract excerpt

This review highlights the basic paradigms and directions of molecular genetic studies of cognitive deficits in schizophrenia. Along with the traditional approach based on functional candidate genes, it covers genome-wide association studies (GWAS) for cognition in general population and schizophrenic patients, attempts to integrate GWAS results in polygenic profiles that can be used in personalized care of...

Topics

Cognition
Cognition Disorders
Cognitive Dysfunction
Epigenesis, Genetic
Genome-Wide Association Study
Humans
Polymorphism, Single Nucleotide
Schizophrenia

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 28635752
DOI: 10.17116/jnevro2016116111137-144

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