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Human Cytomegalovirus-Infected Glioblastoma Cells Display Stem Cell-Like Phenotypes

22 Jun 2017

Abstract excerpt

A role for HCMV in GBMs remains controversial for several reasons. Some studies find HCMV in GBM tumors, while others do not. Few cells within a GBM may harbor HCMV, making it unclear how the virus could be contributing to the tumor phenotype without infecting every cell. Finally, HCMV does not overtly transform cells in vitro . However, tumors induced by other viruses can be treated with antiviral remedies, and...

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PMID: 28656174
DOI: 10.1128/msphere.00137-17

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