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Two Variants in SLC24A5 Are Associated with "Tiger-Eye" Iris Pigmentation in Puerto Rican Paso Fino Horses.

G3 (Bethesda, Md.) - 7 Aug 2017

Mack Maura, Kowalski Elizabeth, Grahn Robert, Bras Dineli, Penedo Maria Cecilia T, Bellone Rebecca

Abstract excerpt

A unique eye color, called tiger-eye, segregates in the Puerto Rican Paso Fino (PRPF) horse breed and is characterized by a bright yellow, amber, or orange iris. Pedigree analysis identified a simple autosomal recessive mode of inheritance for this trait. A genome-wide association study (GWAS) with 24 individuals identified a locus on ECA 1 reaching genome-wide significance (Pcorrected = 1.32 × 10-5). This ECA1...

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PMID: 28655738
DOI: 10.1534/g3.117.043786
PMCID: PMC5555483

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