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Article

Targeting of regulated necrosis in kidney disease

22 Jun 2017

Abstract excerpt

The term acute tubular necrosis was thought to represent a misnomer derived from morphological studies of human necropsies and necrosis was thought to represent an unregulated passive form of cell death which was not amenable to therapeutic manipulation. Recent advances have improved our understanding of cell death in acute kidney injury. First, apoptosis results in cell loss, but does not trigger an inflammatory...

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PMID: 28647049
DOI: 10.1016/j.nefro.2017.04.004

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