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Article

The pathological features of regulated necrosis

4 Feb 2019

Abstract excerpt

Necrosis of a cell is defined by the loss of its plasma membrane integrity. Morphologically, necrosis occurs in several forms such as coagulative necrosis, colliquative necrosis, caseating necrosis, fibrinoid necrosis, and others. Biochemically, necrosis was demonstrated to represent a number of genetically determined signalling pathways. These include (i) kinase-mediated necroptosis, which depends on receptor...

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PMID: 30714148
DOI: 10.1002/path.5248

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