Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role and mechanism of autophagy‐regulating factors in tumorigenesis and drug resistance

24 Sept 2020

Abstract excerpt

A hallmark feature of tumorigenesis is uncontrolled cell division. Autophagy is regulated by more than 30 genes and it is one of several mechanisms by which cells maintain homeostasis. Autophagy promotes cancer progression and drug resistance. Several genes play important roles in autophagy-induced tumorigenesis and drug resistance including Beclin-1, MIF, HMGB1, p53, PTEN, p62, RAC3, SRC3, NF-2, MEG3, LAPTM4B,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine and Purinergic Signaling
Share to Autophagy in Disease and Therapy
Share to Cancer-related gene regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32970929
DOI: 10.1111/ajco.13449

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role and mechanism of autophagy‐regulating factors in tumorigenesis and drug resistancePMID 32970929Read ↗

Molecular Mechanisms of Autophagy in Cancer Development, Progression, and TherapySemantic proximity Read ↗

Autophagy: A novel mechanism of chemoresistance in cancersSemantic proximity Read ↗

Molecular Mechanisms Underlying Autophagy-Mediated Treatment Resistance in CancerSemantic proximity Read ↗

Autophagy-related signaling pathways are involved in cancer (Review)Semantic proximity Read ↗

Autophagy-related lncRNAs in tumor progression and drug resistance: A double-edged swordSemantic proximity Read ↗

Autophagy: New Insights into Its Roles in Cancer Progression and Drug ResistanceSemantic proximity Read ↗

Autophagy signaling in cancer and its potential as novel target to improve anticancer therapySemantic proximity Read ↗

Autophagy and tumorigenesisSemantic proximity Read ↗

Targeting Autophagy to Overcome Drug Resistance in Cancer TherapySemantic proximity Read ↗

The role of autophagy in cancer development and response to therapySemantic proximity Read ↗

Autophagy and cancer – issues we need to digestSemantic proximity Read ↗

Autophagy in cancer development, immune evasion, and drug resistanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.