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Article

Gene expression study of mitochondrial complex I in schizophrenia and paranoid personality disorder.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Jan 2018

Haghighatfard Arvin, Andalib Sarah, Amini Faskhodi Mozhdeh, Sadeghi Soha, Ghaderi Amir Hossein, Moradkhani Shadi, Rostampour Jalal, Tabrizi Zeinab, Mahmoodi Ali, Karimi Talie, Ghadimi Zakieh

Abstract excerpt

OBJECTIVES: The aetiology and molecular mechanisms of schizophrenia (SCZ) and paranoid personality disorder (PPD) are not yet clarified. The present study aimed to assess the role of mitochondrial complex I and cell bioenergetic pathways in the aetiology and characteristics of SCZ and PPD. METHODS: mRNA levels of all genomic and mitochondrial genes which encode mitochondrial complex I subunits (44 genes) were...

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PMID: 28635542
DOI: 10.1080/15622975.2017.1282171

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