Article
Evolutionary radiation of lanthipeptides in marine cyanobacteria.
Proceedings of the National Academy of Sciences of the United States of America - 3 Jul 2017
Cubillos-Ruiz Andres, Berta-Thompson Jessie W, Becker Jamie W, van der Donk Wilfred A, Chisholm Sallie W
Abstract excerpt
Lanthipeptides are ribosomally derived peptide secondary metabolites that undergo extensive posttranslational modification. Prochlorosins are a group of lanthipeptides produced by certain strains of the ubiquitous marine picocyanobacteria Prochlorococcus and Synechococcus Unlike other lanthipeptide-producing bacteria, picocyanobacteria use an unprecedented mechanism of substrate promiscuity for the production of...
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