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Article

Phenotype databases for genetic screens in human cells.

Journal of biotechnology - 10 Nov 2017

Rauscher Benedikt, Valentini Erica, Hardeland Ulrike, Boutros Michael

Abstract excerpt

Genetic screens are powerful tools to identify components that make up biological systems. Perturbations introduced by methods such as RNA interference (RNAi) or CRISPR/Cas9-mediated genome editing lead to biological phenotypes that can be examined to understand the molecular function of genes in the cell. Over the years, many of such experiments have been conducted providing a wealth of knowledge about...

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PMID: 28625679
DOI: 10.1016/j.jbiotec.2017.06.008

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