Article
Patterns of initial and intracranial failure in metastatic EGFR-mutant non-small cell lung cancer treated with erlotinib.
Lung cancer (Amsterdam, Netherlands) - 1 Jun 2017
Patel Suchit H, Rimner Andreas, Foster Amanda, Zhang Zhigang, Woo Kaitlin M, Yu Helena A, Riely Gregory J, Wu Abraham J
Abstract excerpt
OBJECTIVES: Patients with metastatic EGFR-mutant (mEGFRmt) NSCLC have favorable survival when treated with erlotinib. We hypothesized that treatment failure in most patients is limited to initial sites of disease, in which case incorporating local therapy such as radiation might further delay progression. We therefore analyzed patterns and predictors of failure in a large cohort of such patients. MATERIALS AND...
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