Article
Pattern of Recurrence Analysis in Metastatic EGFR-Mutant NSCLC Treated with Osimertinib: Implications for Consolidative Stereotactic Body Radiation Therapy.
International journal of radiation oncology, biology, physics - 1 May 2020
Guo Tiantian, Ni Jianjiao, Yang Xi, Li Yuan, Li Yida, Zou Liqing, Wang Shengping, Liu Quan, Chu Li, Chu Xiao, Li Shuyan, Ye Luxi, Zhu Zhengfei
Abstract excerpt
PURPOSE: Despite the impressive response rate to osimertinib, acquired resistance remains an obstacle to achieving long-term tumor control in metastatic epidermal growth factor receptor-mutant non-small cell lung cancer. Stereotactic body radiation therapy (SBRT) plays a growing role in the management of oligometastatic disease. We investigated the patterns of residual disease and progression on osimertinib, as...
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