Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SOX2 regulates acinar cell development in the salivary gland

17 Jun 2017

Abstract excerpt

Acinar cells play an essential role in the secretory function of exocrine organs. Despite this requirement, how acinar cells are generated during organogenesis is unclear. Using the acini-ductal network of the developing human and murine salivary gland, we demonstrate an unexpected role for SOX2 and parasympathetic nerves in generating the acinar lineage that has broad implications for epithelial morphogenesis....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axon Guidance and Neuronal Signaling
Share to Proteoglycans and glycosaminoglycans research
Share to Salivary Gland Disorders and Functions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28623666
DOI: 10.7554/elife.26620

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SOX2 regulates acinar cell development in the salivary glandPMID 28623666Read ↗

Salivary glands regenerate after radiation injury through SOX2‐mediated secretory cell replacementSemantic proximity Read ↗

Ascl3 expression marks a progenitor population of both acinar and ductal cells in mouse salivary glands.Semantic proximity Read ↗

Salivary gland development and diseaseSemantic proximity Read ↗

Epithelial Cell Lineage and Signaling in Murine Salivary GlandsSemantic proximity Read ↗

FGFR2b is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiationSemantic proximity Read ↗

Salivary gland stem cells: A review of development, regeneration and cancerSemantic proximity Read ↗

Salivary gland function, development, and regenerationSemantic proximity Read ↗

Generation of salivary glands derived from pluripotent stem cells via conditional blastocyst complementationSemantic proximity Read ↗

sox9b Is a Key Regulator of Pancreaticobiliary Ductal System DevelopmentSemantic proximity Read ↗

Salivary gland organogenesisSemantic proximity Read ↗

Overview of Human Salivary Glands: Highlights of Morphology and Developing ProcessesSemantic proximity Read ↗

Bottom-up assembly of salivary gland microtissues for assessing myoepithelial cell function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.