Article
Cell fate decisions during neural crest ontogeny.
The International journal of developmental biology - 1 Jan 2017
Kalcheim Chaya, Kumar Deepak
Abstract excerpt
The neural crest (NC) originates in the central nervous system (CNS) primordium. Born as an epithelium, NC progenitors undergo an epithelial-to-mesenchymal transition that generates cellular movement away from the CNS. Mesenchymal NC progenitors then migrate through stereotypic pathways characteristic of various axial levels until homing to distinct primordia where phenotypic differentiation takes place. Being...
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