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The Hope and Hype of CRISPR-Cas9 Genome Editing

14 Jun 2017

Abstract excerpt

Importance: Clustered regularly interspaced short palindromic repeats (CRISPR) CRISPR-associated protein 9 (CRISPR-Cas9) has garnered a great degree of attention since its first reported uses in mammalian cells in early 2013 due to its perceived impact with respect to potential research applications and, especially, therapeutic applications. Observations: CRISPR-Cas9 is being widely used in the laboratory and has...

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Identifiers

PMID: 28614576
DOI: 10.1001/jamacardio.2017.1713

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