Article
Urinary metabolic insights into host-gut microbial interactions in healthy and IBD children.
World journal of gastroenterology - 28 May 2017
Martin Francois-Pierre, Su Ming-Ming, Xie Guo-Xiang, Guiraud Seu Ping, Kussmann Martin, Godin Jean-Philippe, Jia Wei, Nydegger Andreas
Abstract excerpt
AIM: To identify metabolic signatures in urine samples from healthy and inflammatory bowel disease (IBD) children. METHODS: We applied liquid chromatography and gas chromatography coupled to targeted mass spectrometry (MS)-based metabolite profiling to identify and quantify bile acids and host-gut microbial metabolites in urine samples collected from 21 pediatric IBD patients monitored three times over one year...
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