Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Development of next generation sequencing panel for UMOD and association with kidney disease.

PloS one - 1 Jan 2017

Bailie Caitlin, Kilner Jill, Maxwell Alexander P, McKnight Amy Jayne

Abstract excerpt

Chronic kidney disease (CKD) has a prevalence of approximately 10% in adult populations. CKD can progress to end-stage renal disease (ESRD) and this is usually fatal unless some form of renal replacement therapy (chronic dialysis or renal transplantation) is provided. There is an inherited predisposition to CKD with several genetic risk markers now identified. The UMOD gene has been associated with CKD of varying...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CpG Islands
Share to Disease Progression
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kidney Failure, Chronic

Share to Linkage Disequilibrium

Share to Regulatory Sequences, Nucleic Acid

Share to Renal Insufficiency, Chronic

Share to Uromodulin

Source

Open in PubMed Open full text

Identifiers

PMID: 28609449
DOI: 10.1371/journal.pone.0178321
PMCID: PMC5469457

Genes

UMOD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development of next generation sequencing panel for UMOD and association with kidney disease.PMID 28609449Read ↗

The UMOD Locus: Insights into the Pathogenesis and Prognosis of Kidney Disease.Semantic proximity Read ↗

Assessment of differentially methylated loci in individuals with end-stage kidney disease attributed to diabetic kidney diseaseSemantic proximity Read ↗

Assessment of differentially methylated loci in individuals with end-stage kidney disease attributed to diabetic kidney disease: an exploratory studySemantic proximity Read ↗

Association of variants at UMOD with chronic kidney disease and kidney stones-role of age and comorbid diseases.Semantic proximity Read ↗

DNA hypermethylation and DNA hypomethylation is present at different loci in chronic kidney diseaseSemantic proximity Read ↗

Next-generation sequencing for research and diagnostics in kidney diseaseSemantic proximity Read ↗

UMOD and the architecture of kidney diseaseSemantic proximity Read ↗

An intermediate effect size variant in <i>UMOD</i> confers risk for chronic kidney diseaseSemantic proximity Read ↗

Association of estimated glomerular filtration rate and urinary uromodulin concentrations with rare variants identified by UMOD gene region sequencing.Semantic proximity Read ↗

Genomic approaches in the search for molecular biomarkers in chronic kidney diseaseSemantic proximity Read ↗

UMOD Polymorphisms Associated with Kidney Function, Serum Uromodulin and Risk of Mortality among Patients with Chronic Kidney Disease, Results from the C-STRIDE Study.Semantic proximity Read ↗

UMOD Polymorphisms Associated With Kidney Function, Serum Uromodulin and Risk of Mortality Among Patients With Chronic Kidney Disease, Results From the C-STRIDE studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.