Article
An esophageal squamous cell carcinoma classification system that reveals potential targets for therapy.
Oncotarget - 25 Jul 2017
Xiong Teng, Wang Mengyao, Zhao Jing, Liu Qing, Yang Chao, Luo Wen, Li Xiangchun, Yang Huanming, Kristiansen Karsten, Roy Bhaskar, Zhou Yong
Abstract excerpt
ESCC (Esophageal squamous cell carcinoma) is a heterogeneous cancer with diverse prognosis. Here, to explore the biological diversity of ESCC, we employed gene expression profiles from 360 ESCC tumors from East Asians to establish a comprehensive molecular classification and characterization of ESCC. Using the specific 185-gene signature generated by unsupervised consensus clustering of gene expression data, we...
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