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Article

OUP accepted manuscript

1 Jan 2017

Abstract excerpt

Resistance to antifungals is a leading concern in the treatment of human mycoses. We demonstrate that the salA gene, encoding salicylate 1-monooxygenase, is involved in resistance of the dermatophyte Trichophyton rubrum to terbinafine, one of the most effective antifungal drugs against dermatophytes. A strain with multiple copies of salA was constructed and exhibited elevated expression of salA and increased...

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Identifiers

PMID: 28582544
DOI: 10.1093/mmy/myx044

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