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Article

Upregulated energy metabolism in the Drosophila mushroom body is the trigger for long-term memory.

Nature communications - 5 Jun 2017

Plaçais Pierre-Yves, de Tredern Éloïse, Scheunemann Lisa, Trannoy Séverine, Goguel Valérie, Han Kyung-An, Isabel Guillaume, Preat Thomas

Abstract excerpt

Efficient energy use has constrained the evolution of nervous systems. However, it is unresolved whether energy metabolism may resultantly regulate major brain functions. Our observation that Drosophila flies double their sucrose intake at an early stage of long-term memory formation initiated the investigation of how energy metabolism intervenes in this process. Cellular-resolution imaging of energy metabolism...

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PMID: 28580949
DOI: 10.1038/ncomms15510
PMCID: PMC5465319

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