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Evaluation of comprehensive chromosome screening platforms for the detection of mosaic segmental aneuploidy

2 Jun 2017

Abstract excerpt

PURPOSE: A subset of preimplantation embryos identified as euploid may in fact possess both whole and sub-chromosomal mosaicism, raising concerns regarding the predictive value of current comprehensive chromosome screening (CCS) methods utilizing a single biopsy. Current CCS methods may be capable of detecting sub-chromosomal mosaicism in a trophectoderm biopsy by examining intermediate levels of segmental...

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PMID: 28577183
DOI: 10.1007/s10815-017-0924-4

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