Article
[Determination of drug resistance mutations of NS3 inhibitors in chronic hepatitis C patients infected with genotype 1].
Mikrobiyoloji bulteni - 1 Apr 2017
Şanlıdağ Tamer, Sayan Murat, Akçalı Sinem, Kasap Elmas, Buran Tahir, Arıkan Ayşe
Abstract excerpt
Direct-acting antiviral agents (DAA) such as NS3 protease inhibitors is the first class of drugs used for chronic hepatitis C (CHC) treatment. NS3 inhibitors (PI) with low genetic barrier have been approved to be used in the CHC genotype 1 infections, and in the treatment of compensated liver disease including cirrhosis together with pegile interferon and ribavirin. Consequently, the development of drug...
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