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Article

C9orf72 mutations do not influence the tau signature of amyotrophic lateral sclerosis with cognitive impairment (ALSci).

Amyotrophic lateral sclerosis & frontotemporal degeneration - 1 Nov 2017

Volkening Kathryn, Strong Wendy L, Seaton Shauntel, Yang Wencheng, Strong Michael J

Abstract excerpt

OBJECTIVE: C9orf72 mutations are associated with amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and ALS-FTD. In addition to ALS-FTD, ALS patients may develop a spectrum of neuropsychological and neuropsychiatric deficits including ALS with cognitive impairment (ALSci). Here we examine the extent to which C9orf72 mutations are associated with ALSci and whether this alters the tau molecular...

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Identifiers

PMID: 28562075
DOI: 10.1080/21678421.2017.1332075

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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