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Article

Factors associated with risk of central nervous system relapse in patients with non-core binding factor acute myeloid leukemia.

American journal of hematology - 1 Sept 2017

Jabbour Elias, Guastad Daver Naval, Short Nicholas James, Huang Xuelin, Chen Hsiang-Chun, Maiti Abhishek, Ravandi Farhad, Cortes Jorge, Abi Aad Simon, Garcia-Manero Guillermo, Estrov Zeev, Kadia Tapan, O'Brien Susan, Dabaja Bouthaina, Bueso-Ramos Carlos, Strati Paolo, Bivins Carol, Pierce Sherry, Kantarjian Hagop

Abstract excerpt

Central nervous system (CNS) relapse is uncommon in patients with acute myeloid leukemia (AML) with the use of high-dose cytarabine containing chemotherapy regimens. The clinical and molecular features associated with a higher risk of CNS relapse are not well defined. We assessed the incidence and outcome of CNS relapses among 1245 patients with relapsed/refractory AML referred to our institution between 2000 and...

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Identifiers

PMID: 28556489
DOI: 10.1002/ajh.24799
PMCID: PMC5901967

Genes

FLT3

Provenance

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