Article
Splicing-related single nucleotide polymorphism of RAB, member of RAS oncogene family like 2B (RABL2B) jeopardises semen quality in Chinese Holstein bulls.
Reproduction, fertility, and development - 1 Nov 2017
Wang Xiuge, Cui Xiaohui, Zhang Yan, Hao Haisheng, Ju Zhihua, Liu Deyu, Jiang Qiang, Yang Chunhong, Sun Yan, Wang Changfa, Huang Jinming, Zhu Huabin
Abstract excerpt
RAB, member of RAS oncogene family like 2B (RABL2B) is a member of a poorly characterised clade of the RAS GTPase superfamily, which plays an essential role in male fertility, sperm intraflagellar transport and tail assembly. In the present study, we identified a novel RABL2B splice variant in bovine testis and spermatozoa. This splice variant, designated RABL2B-TV, is characterised by exon 2 skipping. Moreover,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.